Steven S. Juhn, MD

Professor of Otolarynglogy and Director of the Auditory Biochemistry Laboratory, Department of Otolaryngology, Head and Neck Surgery

Steven S. Juhn

Contact Info

juhnx001@umn.edu

Office Phone 612-626-9879

Office Address:
Otolaryngology
107 Lions Res
2001 6th St SE
Minneapolis, MN 55455

Mailing Address:
Otolaryngology
LRB/MTRF
2873D (Campus Delivery Code)
2001 6th St SE
Minneapolis, MN 55455

Professor of Otolarynglogy and Director of the Auditory Biochemistry Laboratory, Department of Otolaryngology, Head and Neck Surgery


MD, Kyungpook National University, Korea

MS, Seoul National University, Korea

Research

Research Summary/Interests

  1. Pathogenesis of otitis media and new treatment design
  2. Biochemistry of inner ear fluids and tissues (blood-labyrinth barrier)
  3. Pathogenesis of Meniere’s disease
  4. Mechanisms of age-related hearing loss and management
  5. Repair of inner ear organs by stem cell implantation

Publications

Selected Publications

  • Heman-Ackah SE, Juhn SK, Huang TC, Wiedmann TS. A combination antioxidant therapy prevents age-related hearing loss in C57BL/6 mice. Arch Otolaryngol Head Neck Surg. 143:429-434, 2010.
  • Schachern PA, Tsuprun V, Cureoglu S, Ferrieri P, David E Briles DE, Paparella MM, Juhn SK. Effect of apolactoferrin on experimental pneumococcal otitis media. Arch Otolaryngol Head Neck Surg 136(11), 1127-31, 2010. PMID: 21079169
  • Joglekar S, Morita N, Cureoglu S, Schachern PA, Deroe AF, Tsuprun V, Paparella, MM, Juhn S. Cochlear pathology in human temporal bones with otitis media. Acta Otolaryngologica 130(4):472-476, 2010. PMID: 19895333.
  • Schachern PA, Tsuprun V, Cureoglu S, Wang B, Apicella MA, Paparella MM, Juhn SK. Effect of lipooligosaccharide mutations of Haemophilus influenzae on the middle and inner ears. Int J Pediatr Otorhinolaryngol 73(12):1757-60, 2009. PMID: 19853312.
  • Schachern PA, Tsuprun V, Cureoglu S, Ferrieri P, Briles DE. Paparella M, Juhn S. Virulence of the pneumococcal proteins on the inner ear. Arch Otolaryngol Head Neck Surg 135(7):653-657, 2009. PMID: 19620586.
  • Tsuprun V, Cureoglu S, Schachern PA, Ferrieri P, Briles DE, Paparella MM, Junh SK. Role of pneumococcal proteins in the sensorineural hearing loss due to otitis media. Otol Neurotol 29(8):1056-1060, 2008. PMID: 18833010.
  • Schachern PA, Tsuprun V, Cureoglu S, Ferrieri P, Briles DE, Paparella MM, Juhn S. The round window membrane in otitis media. Effect of pneumococcal proteins. Otolaryngol Head Neck Surg 134:658-662, 2008. PMID: 18559736.
  • Karya S, Schachern P, Cureoglu S, Tsuprun V, Okano M, Kazunori N, Juhn S. Up-regulation of macrophage inhibitory factor induced by endotoxin in experimental otitis media with effusion in mice. Acta Oto-Laryngol 128(7):750-755, 2008. PMID: 18568516.
  • Anderson JH, Juhn SK: Stem cell strategies for treating inner ear dysfunction (Chapter 15). In: Stem Cell and Regenerative Medicine. Low W and Verfaillie CM, Eds), World Scientific, 2008.
  • Juhn SK, Hunter BA, Odland RM. Blood-labyrinth barrier and fluid dynamics of the inner ear. Int Tinnitus J 7:72-83, 2001.
  • Juhn SK, Li W, Kim JY, Javel E, Levine S, Odland RM. Effect of stress-related hormones on inner ear fluid homeostasis and function. Am J Otology 20:800-806, 1999.

Abstracts

  • Juhn SK, Lee JE, Jung MK, Tsuprun V, Schachern PA. Age-related changes in the rat cochlear lateral wall. Association for Research in Otolaryngology February 2006.
  • Juhn SK, Kim BH, Schachern PA, Adams GL. Blood labyrinth barrier permeability assessment by Evans Blue extravasation. Association for Research in Otolaryngology February 2005.
  • Jurney WM, Oh S, Keene CD, Ortiz-Gonzalez XR, Low WC, Verfaillie CM, Juhn SK, Anderson JH. Survival and distribution of adult-derived stem cells transplanted into the adult mouse inner ear. Association for Research in Otolaryngology February 2003.
  • Juhn SK, Lee YW, Ge M, Hunter BA, Lee SH, Odland R. The role of lateral wall pathology in hearing loss of aged animals. Association for Research in Otolaryngology February 2002.
  • Juhn SK, Hunter BA, Odland RM. Estimation of perilymph concentration of agents applied to round window membrane by microdialysis. Association for Research in Otolaryngology February 2001.
  • Kim DJ, Li W, Juhn SK. Role of reactive oxygen species and antioxidant system. Association for Research in Otolaryngology February 2000.