We bring together talent and expertise from across the University of Minnesota to use stem cell biology to advance regenerative medicine therapies for devastating disorders and to provide education and training for the stem cell scientists of tomorrow.


Come see us at the State Fair (and maybe get a free backpack)!

On August 29, 2016, we will be at the Crossroads Building at the Great Minnesota Get-Together from 9:00 AM to 3:00 PM. Please stop by, learn more about us, and check out our giveaways! We hope to see you there!Goldy Gopher Thumbs up

Our Research

McGuire Translational Research Facility gets a new look!

Driven to Transform Health CareEver wonder what an induced pluripotent stem cell looks like? Stop by 2001 6th St SE and look up! The new Driven to Transform Health Care window graphic has been installed. At the bottom, the blue and green structure is an induced pluripotent stem cell that has been instructed to become a neural cell.

induced pluripotent stem cellThe University depends on the wide array of skills of its scientists. The original image below was taken by expert microscope photographer Megan Riddle. It takes serious skills to get a picture of a cell that can be enlarged to 12 feet high!



Our Education Programs

The bioscience and medical industries and academic research programs need intelligent, engaged, well-trained talent to fill jobs in the rapidly expanding field of regenerative medicine. The Stem Cell Institute prepares students who are ready to meet this need and who are eager to move the next generation of research forward. Learn more about our graduate programs:

In the News

Food and Drug Administration logo
July 18, 2016

The Stem Cell Institute receives many inquiries from patients wanting to know if stem cell therapies are safe and available to help them. It can be confusing to sort out what is claimed from what has been proven. In February The Food and Drug Administration issued draft guidelines clarifying that the stem cells used in most clinics are drugs and require a rigorous approval process before they can be used in patients. Read the FDA Consumer Update on stem cell therapies. In September 2016, the FDA will be holding public meetings to hear comments on the draft guidelines.

Patients considering stem cell therapies can find reputable information at the International Society for Stem Cell Research (ISSCR) website: www.closerlookatstemcells.org.

Jim Gass
June 23, 2016

Jim Gass received a stem cell treatment in Mexico in the hopes of improving after a stroke. The devastating outcome of this procedure is outlined in this article from The New York Times.

Here at the SCI, we do not treat patients--we perform the basic science research that is needed to find promising new treatments and to establish that they are safe and effective--but we do we receive many inquiries about stem cell therapies. We want to help everyone get accurate information as they educate themselves. Stem cells hold incredible potential but, as this article illustrates, we have much to learn about them that is better learned in a laboratory rather than at a patient's expense.

We suggest you also visit www.closerlookatstemcells.org, a reputable site published by the International Society for Stem Cell Research (ISSCR). Further information of interest on this topic includes an article from the Washington Post and an advisory from the FDA.

Regenerative Medicine Minnesota logo
May 23, 2016

Regenerative Medicine Minnesota is working to create the infrastructure and knowledge needed to bring regenerative therapies to Minnesotans and to bring Minnesota to the forefront of regenerative medicine. The second year's funding of Educational Programs and Biobusiness/Biotechnology are announced today.

Spinal Cord Society Image of Cells
April 28, 2016

Drs. Eric Holmberg, PhD, Research Director of the Spinal Cord Society, and Shu-xin Zhang, MD, PhD, a contracted researcher with the Spinal Cord Society, will be spending time at Dr. Ann Parr's Stem Cell Institute lab this week to start work on their collaboration for a combination therapy to treat chronic spinal cord injury. Drs. Holmberg and Zhang will be demonstrating their technique to ablate the glial scar that develops at the site of injury using a photo-toxic chemical probe called rose-Bengal. Scar ablation provides a more permissive physical and biochemical environment for axon sprouting. Once the technique is optimized, human induced pluripotent stem cell (hIPSC) derived oligodendrocyte precursor cells (OPCs) derived by Dr. Parr's lab will be transplanted following scar ablation. The hypothesis is that the cells will survive and integrate into the injured spinal cord and provide functional recovery. 

This collaborative work was recently funded with the Spinal Cord Injury and Traumatic Brain Injury Grant from the Minnesota legislature.

Weekly Research Conference

Meets weekly in Room 1-110
McGuire Translational Research Facility (MTRF, next to Lion's Research Building)
[map] [shuttle schedule]

Wednesday, August 31, 2016 - 4:00pm

Molecular landscape of mesodermal lineage diversification revealed by single cell transcriptomics

Wuming Gong, PhD
Wuming Gong, PhD
Research Associate, Garry Lab, UMN