We bring together talent and expertise from across the University of Minnesota to use stem cell biology to advance regenerative medicine therapies for devastating disorders and to provide education and training for the stem cell scientists of tomorrow.

Our Research

Our Education Programs

The bioscience and medical industries and academic research programs need intelligent, engaged, well-trained talent to fill jobs in the rapidly expanding field of regenerative medicine. The Stem Cell Institute prepares students who are ready to meet this need and who are eager to move the next generation of research forward. Learn more about our graduate programs:

In the News

3D printed head combining both translucent and opaque materials.
February 8, 2016

The University of Minnesota Medical Devices Center has an Objet Connex 260 3D Printer available to create high quality 3D parts. Its ability to use multiple materials in a single applicaion is a great resource for a wide variety of applications:

  • General Prototyping
  • High Detail Models
  • Moving/Dynamic Models
  • Multi-Material Models
  • Functional Mold Testing
  • Suspended Models
Professor Robert Tranquillo
February 2, 2016

Stem Cell Institute faculty member Robert Tranquillo's laboratory is using tissue engineering to develop a heart valve that can grow with children. This would help reduce the number of surgeries these children need to replace outgrown valves. See the whole story at KARE11 news: link.

PDF Cover
January 12, 2016

Dr. Sunny Chan, an Assistant Professor in SCI faculty member Michael Kyba’s lab at the University of Minnesota, has a paper featured on the cover of the ISSCR's journal Stem Cell Reports
"Development of Bipotent Cardiac/Skeletal Myogenic Progenitors from MESP1+ Mesoderm"

As ancient chordates developed predatory feeding, new muscle tissue was required, both in the face, to enable biting, and in the heart, where new chambers allowed efficient circulation. This advance was enabled by a new population of mesoderm, referred to as cardiopharyngeal mesoderm, CPM, which produces both facial skeletal muscle and cells that will produce the new chambers of the heart (atria and right ventricle). In this paper, Dr. Chan finds a way to generate CPM from pluripotent cells in the Petri dish, and uses these cells to dissect regulatory pathways controlling its differentiation into cardiac or skeletal muscle tissue.

Sunny Sun-Kin Chan, Hannah R. Hagen, Scott A. Swanson, Ron Stewart, Karly A. Boll, Joy Aho, James A. Thomson, and Michael Kyba

Volume 6, Issue 1, p26–34, 12 January 2016

Cover of ISSCR publication: Patient Handbook on Stem Cell Therapies
October 29, 2015

Patients frequently want to know how soon stem cell therapies will be available, or if a therapy they have heard about is safe. These are important questions. In response, the International Society for Stem Cell Research has published an excellent and helpful handbook: Patient Handbook for Stem Cell Therapies. It includes questions to ask when evaluating a potential therapy.

Weekly Research Conference

Meets weekly in Room 1-110
McGuire Translational Research Facility (MTRF, next to Lion's Research Building)
[map] [shuttle schedule]

Wednesday, February 10, 2016 - 4:00pm

Extracellular Matrix Derived Hydrogels for Regenerative Medicine

Dr. Karen L. Christman

Karen L. Christman, PhD

Associate Professor of Bioengineering
Sanford Consortium for Regenerative Medicine
University of California, San Diego

Wednesday, February 17, 2016 - 4:00pm

Cell Fate Control by Integrated E2F, FOXO, and AKT Signaling in Retinal Progenitor Cells and Retinoblastoma

Timothy Hallstrom

Timothy C. Hallstrom, PhD

Assistant Professor
Department of Pediatrics
University of Minnesota

Wednesday, February 24, 2016 - 4:00pm

Chemical Control of Oligodendrocyte Fate and Function

Paul Tesar

Paul Tesar, PhD

Associate Professor
Department of Genetics & Genome Sciences
Case Western Reserve University
Cleveland, Ohio