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We bring together talent and expertise from across the University of Minnesota to use stem cell biology to advance regenerative medicine therapies for devastating disorders and to provide education and training for the stem cell scientists of tomorrow.

Welcome

Our Research

We depend on the variety of knowledge and expertise from faculty and departments across the University and beyond to pursue the collaborative goal of using stem cell technology to change the practice of regenerative medicine.

SCI scientists are making progress in finding treatments for spine and brain injury, heart damage, vision loss, diabetes, genetic disorders, cancer, and the need for organ and skin replacement. Learn more about:

Our Education Programs

The bioscience and medical industries and academic research programs need intelligent, engaged, well-trained talent to fill jobs in the rapidly expanding field of regenerative medicine. The Stem Cell Institute prepares students who are ready to meet this need and who are eager to move the next generation of research forward. Learn more about our graduate programs:

  • Wei-Shou Hu, PhD

    Professor

  • Andrew Grande, MD

    Assistant Professor

  • Steven S. Juhn, MD

    Professor

  • In the News

    May 16, 2017

    blood cells

    An exciting development in understanding how cancer works and potential ways of blocking it occurred recently in Dr. Rita Perlingeiro's laboratory. A new study in Blood shows that a glycoprotein on the cell surface called endoglin, also known as CD105, is a marker for the cancer stem cell in acute myeloid leukemia (AML) and acute B-lymphoblastic leukemia (B-ALL), suggesting it plays a role in its genesis.

    After discovering this feature, lead researcher Rita Perlingeiro, PhD, professor in the University of Minnesota Medical School’s Department of Medicine and Stem Cell Institute Faculty member, then tested whether targeting endoglin would halt the progression of leukemia.  

    Randy Mills Photo
    May 2, 2017

    The head of California's stem-cell agency is stepping down after three years. C. Randall Mills, known as Randy, is leaving the agency to run a nonprofit bone marrow donor matching program as of July 1, according to the California Institute of Regenerative Medicine.  “Mills had a big positive impact on CIRM and helped it go to the next level,” writes Paul Knoepfler, a stem-cell researcher at the University of California, Davis, and close chronicler of regenerative medicine science and policy at his blog The Niche.

    Molly Kupfer and Brenda Ogle
    April 18, 2017

    Brenda Ogle, PhD, a Stem Cell Institute faculty member and associate professor of biomedical engineering, is part of a team that has created a revolutionary 3D-bioprinted patch that can help heal scarred heart tissue after a heart attack.  The team is comprised of researchers from UMN, University of Wisconsin-Madison and the University of Alabama-Birmingham.  Researchers used laser-based 3D-bioprinting techniques to incorporate stem cells derived from adult human heart cells on a matrix that began to grow and beat synchronously in a dish in the lab.  Read more about the study published recently in Circulation Research.

    April 11, 2017

    On April 10, Regenerative Medicine Minnesota (RMM) announced awards. Congratulations to the following SCI Faculty

    Research Grant Awards 

    • Karen Echeverri, PhD - Spinal Cord Regeneration: Translating from Salamanders to Enhance Regenerative Repair after Injury in Mammals 
    • Mark J. Osborn, PhD - Natural Killer Cell Chimeric Antigen Receptor Therapy
    • Jop van Berlo, PhD - Identification of Novel Regulators of Heart Regeneration

    Educational Grant Award

    Troy Lund, MD, PhD - Medical Student Summer Research Program in Regenerative Medicine - Pre-T35

    Biobusiness Grant Awards

    • James Dutton, PhD - Critical infrastructure to support new stem cell-derived treatments for patients with age-related macular degeneration in Minnesota
    • Walter Low, PhD - Production of Dopamine Neurons – A Cellular Product for Treating Parkinson’s

    Weekly Research Conference

    Meets weekly in Room 1-110
    McGuire Translational Research Facility (MTRF, next to Lion's Research Building)
    [map] [shuttle schedule]

    Wednesday, May 24, 2017 - 4:00pm

    University of Minnesota T32 Grant Trainees

    Cat Lee and Keith SabinCatherine Lee - "Modeling and rescue of defective blood-brain barrier function of brain microvascular endothelial cells from childhood adrenoleukodystrophy patients"

    Keith Sabin - "Molecular mechanisms of spinal cord regeneration in the axolotl"

    Wednesday, May 24, 2017 - 4:00pm

    Leukemia Stem Cell Evolution

    Catronia Jamieson photo

    Dr. Catronia Jamieson, MD/PhD
    Associate Professor

    Department of Medicine/Hematology-0ncology
    University of California, San Diego
    San Diego, CA