We bring together talent and expertise from across the University of Minnesota to use stem cell biology to advance regenerative medicine therapies for devastating disorders and to provide education and training for the stem cell scientists of tomorrow.
We depend on the variety of knowledge and expertise from faculty and departments across the University and beyond to pursue the collaborative goal of using stem cell technology to change the practice of regenerative medicine.
SCI scientists are making progress in finding treatments for spine and brain injury, heart damage, vision loss, diabetes, genetic disorders, cancer, and the need for organ and skin replacement. Learn more about:
Our Education Programs
The bioscience and medical industries and academic research programs need intelligent, engaged, well-trained talent to fill jobs in the rapidly expanding field of regenerative medicine. The Stem Cell Institute prepares students who are ready to meet this need and who are eager to move the next generation of research forward. Learn more about our graduate programs:
In the News
Dr. Timothy O'Brien, UMN professor and Stem Cell Institute member, recently commented on a product, Cell-Mate 3D, that is produced in Two Harbors, MN by BRTI. He described his work growing "cerebral organoids, not just brain cells, as has been done before, but fully formed, albeit microscopic, brain structures" in this relatively new three-dimensional medium rather than the traditional flat, hard bottom of a petri dish." "This is potentially really important because they could be used for development of drugs for neurological problems — to check for toxic effects of drugs," said the University of Minnesota professor and member of the school's Stem Cell Institute. "What we're forming is much more like a real brain than what people have had access to before."
Andrew Grande, M.D. of the UMN Medical School, Department of Neursurgery, and Stem Cell Institute faculty member discusses stroke awareness month on Sunday, May 14 on Roshini Rajkumar's WCCO radio show. He shares information about strokes and educates the audience about what to do if someone thinks they are having a stroke.
An exciting development in understanding how cancer works and potential ways of blocking it occurred recently in Dr. Rita Perlingeiro's laboratory. A new study in Blood shows that a glycoprotein on the cell surface called endoglin, also known as CD105, is a marker for the cancer stem cell in acute myeloid leukemia (AML) and acute B-lymphoblastic leukemia (B-ALL), suggesting it plays a role in its genesis.
After discovering this feature, lead researcher Rita Perlingeiro, PhD, professor in the University of Minnesota Medical School’s Department of Medicine and Stem Cell Institute Faculty member, then tested whether targeting endoglin would halt the progression of leukemia.
The head of California's stem-cell agency is stepping down after three years. C. Randall Mills, known as Randy, is leaving the agency to run a nonprofit bone marrow donor matching program as of July 1, according to the California Institute of Regenerative Medicine. “Mills had a big positive impact on CIRM and helped it go to the next level,” writes Paul Knoepfler, a stem-cell researcher at the University of California, Davis, and close chronicler of regenerative medicine science and policy at his blog The Niche.
Weekly Research Conference
Wednesday, June 28, 2017 - 4:00pm
5th Annual Engineering-Stem Cell Institute Symposium
12 pm Lunch & Poster session
1 pm Key Note Speaker: Dr. Scott Fraser, PhD, USC "Imaging the programs of embryogenesis and organogenesis"
2 pm Presentation: Dr. Jeff Salisbury, PhD, Mayo Clinic "Understanding human disease processes through 3-dimensional electron microscopy of tissue architecture"
2:30 pm Break
3 pm Presentation: Dr. Stan Thayer, PhD, UMN-TC " Longitudinal imaging of synapse loss and recovery"
Wednesday, July 5, 2017 - 4:00pm
No Seminar this week
Wednesday, July 12, 2017 - 3:00pm
Cell changes from conjunctiva to iPS and RPE cells
Zhaohui Geng, PhD
University of Minnesota