We bring together talent and expertise from across the University of Minnesota to use stem cell biology to advance regenerative medicine therapies for devastating disorders and to provide education and training for the stem cell scientists of tomorrow.
We depend on the variety of knowledge and expertise from faculty and departments across the University and beyond to pursue the collaborative goal of using stem cell technology to change the practice of regenerative medicine.
SCI scientists are making progress in finding treatments for spine and brain injury, heart damage, vision loss, diabetes, genetic disorders, cancer, and the need for organ and skin replacement. Learn more about:
Our Education Programs
The bioscience and medical industries and academic research programs need intelligent, engaged, well-trained talent to fill jobs in the rapidly expanding field of regenerative medicine. The Stem Cell Institute prepares students who are ready to meet this need and who are eager to move the next generation of research forward. Learn more about our graduate programs:
In the News
Andrew Grande, M.D. of the UMN Medical School, Department of Neursurgery, and Stem Cell Institute faculty member discusses stroke awareness month on Sunday, May 14 on Roshini Rajkumar's WCCO radio show. He shares information about strokes and educates the audience about what to do if someone thinks they are having a stroke.
An exciting development in understanding how cancer works and potential ways of blocking it occurred recently in Dr. Rita Perlingeiro's laboratory. A new study in Blood shows that a glycoprotein on the cell surface called endoglin, also known as CD105, is a marker for the cancer stem cell in acute myeloid leukemia (AML) and acute B-lymphoblastic leukemia (B-ALL), suggesting it plays a role in its genesis.
After discovering this feature, lead researcher Rita Perlingeiro, PhD, professor in the University of Minnesota Medical School’s Department of Medicine and Stem Cell Institute Faculty member, then tested whether targeting endoglin would halt the progression of leukemia.
The head of California's stem-cell agency is stepping down after three years. C. Randall Mills, known as Randy, is leaving the agency to run a nonprofit bone marrow donor matching program as of July 1, according to the California Institute of Regenerative Medicine. “Mills had a big positive impact on CIRM and helped it go to the next level,” writes Paul Knoepfler, a stem-cell researcher at the University of California, Davis, and close chronicler of regenerative medicine science and policy at his blog The Niche.
Brenda Ogle, PhD, a Stem Cell Institute faculty member and associate professor of biomedical engineering, is part of a team that has created a revolutionary 3D-bioprinted patch that can help heal scarred heart tissue after a heart attack. The team is comprised of researchers from UMN, University of Wisconsin-Madison and the University of Alabama-Birmingham. Researchers used laser-based 3D-bioprinting techniques to incorporate stem cells derived from adult human heart cells on a matrix that began to grow and beat synchronously in a dish in the lab. Read more about the study published recently in Circulation Research.
Weekly Research Conference
Wednesday, May 24, 2017 - 4:00pm
University of Minnesota T32 Grant Trainees
Catherine Lee - "Modeling and rescue of defective blood-brain barrier function of brain microvascular endothelial cells from childhood adrenoleukodystrophy patients"
Keith Sabin - "Molecular mechanisms of spinal cord regeneration in the axolotl"
Wednesday, May 24, 2017 - 4:00pm
Leukemia Stem Cell Evolution
Dr. Catronia Jamieson, MD/PhD