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We bring together talent and expertise from across the University of Minnesota to use stem cell biology to advance regenerative medicine therapies for devastating disorders and to provide education and training for the stem cell scientists of tomorrow.

Welcome

Our Research

We depend on the variety of knowledge and expertise from faculty and departments across the University and beyond to pursue the collaborative goal of using stem cell technology to change the practice of regenerative medicine.

SCI scientists are making progress in finding treatments for spine and brain injury, heart damage, vision loss, diabetes, genetic disorders, cancer, and the need for organ and skin replacement. Learn more about:

Our Education Programs

The bioscience and medical industries and academic research programs need intelligent, engaged, well-trained talent to fill jobs in the rapidly expanding field of regenerative medicine. The Stem Cell Institute prepares students who are ready to meet this need and who are eager to move the next generation of research forward. Learn more about our graduate programs:

In the News

Molly Kupfer and Brenda Ogle
April 18, 2017

Brenda Ogle, PhD, a Stem Cell Institute faculty member and associate professor of biomedical engineering, is part of a team that has created a revolutionary 3D-bioprinted patch that can help heal scarred heart tissue after a heart attack.  The team is comprised of researchers from UMN, University of Wisconsin-Madison and the University of Alabama-Birmingham.  Researchers used laser-based 3D-bioprinting techniques to incorporate stem cells derived from adult human heart cells on a matrix that began to grow and beat synchronously in a dish in the lab.  Read more about the study published recently in Circulation Research.

April 11, 2017

On April 10, Regenerative Medicine Minnesota (RMM) announced awards. Congratulations to the following SCI Faculty

Research Grant Awards 

  • Karen Echeverri, PhD - Spinal Cord Regeneration: Translating from Salamanders to Enhance Regenerative Repair after Injury in Mammals 
  • Mark J. Osborn, PhD - Natural Killer Cell Chimeric Antigen Receptor Therapy
  • Jop van Berlo, PhD - Identification of Novel Regulators of Heart Regeneration

Educational Grant Award

Troy Lund, MD, PhD - Medical Student Summer Research Program in Regenerative Medicine - Pre-T35

Biobusiness Grant Awards

  • James Dutton, PhD - Critical infrastructure to support new stem cell-derived treatments for patients with age-related macular degeneration in Minnesota
  • Walter Low, PhD - Production of Dopamine Neurons – A Cellular Product for Treating Parkinson’s
March 30, 2017

The University of Minnesota is joining the Advanced Regenerative Manufacturing Institute (ARMI), a consortium of nearly 100 organizations spanning industry, government, academia and the non-profit sector.  The Institute is set to receive nearly $300 million in public-private investment to develop scalable manufacturing processes for engineered tissues and organs.  The University will be developing training curricula for 2- and 4-year colleges that will educate educate students about Tissue and Organ Biofabrication, 3D Bioprinting and Regenerative Medicine.

Stem Cell Institute faculty member, Angela Panoskaltsis-Mortari, PhD, led the ARMI submission process for the Midwest region.  She is excited about "being a part of an effort that could benefit patients and our economy."

Human mesenchymal stem cell
March 1, 2017

When scientists can determine what type of cell a stem cell will become, they can better manipulate cells for stem cell therapy.  Scientists at Rutgers and other universities have created a new way to identify the state and fate of stem cells earlier than previously possible.  The approach, called EDICTS (Epi-mark Descriptor Imaging of Cell Transitional States), involves labeling epigenetic modifications and then imaging the cells with super resolution to see the precise location of the marks.

Weekly Research Conference

Meets weekly in Room 1-110
McGuire Translational Research Facility (MTRF, next to Lion's Research Building)
[map] [shuttle schedule]

Wednesday, May 3, 2017 - 12:00pm

Aging and Disease: Stem Cells, Organ Generation and Gene Editing Technologies

photo of JCI Belmonte
 
Professor, The Salk Institute, San Diego, CA
Extraordinary Professor, Catholic University of
San Antonio, Murcia, Spain
 
Co-sponsored by Lillehei Heart Institute

Wednesday, May 10, 2017 - 4:00pm

Immune Control of Regeneration

photo of Nadia Rosenthal
Nadia Rosenthal, PhD/FMedSci
Scientific Director
 
Jackson Laboratory for Mammalian Genetics
Bar Harbor, ME